Khan, Naveed Ahmed * and Ong, Timothy Yu Yee * and Siddiqui, Ruqaiyyah Bano * (2017) Targeting brain-eating amoebae infections. ACS Chemical Neuroscience, 8 (4). pp. 687-688. ISSN 1948-7193
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Official URL: http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7...
Abstract
Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae.
| Item Type: | Article |
|---|---|
| Additional Information: | Embargo 12 months |
| Uncontrolled Keywords: | Protist; free-living amoebae; brain infection; central nervous system; acanthamoeba; balamuthia; naegleria |
| Subjects: | Q Science > Q Science (General) Q Science > QR Microbiology > QR355 Virology |
| Divisions: | Sunway University > School of Engineering and Technology [formerly School of Science and Technology until 2020] > Dept. Biological Sciences moved to SMLS wef 2021 |
| Depositing User: | Dr Janaki Sinnasamy |
| Related URLs: | |
| Date Deposited: | 10 Apr 2017 08:10 |
| Last Modified: | 23 Jan 2020 03:28 |
| URI: | http://eprints.sunway.edu.my/id/eprint/485 |
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