Happy ageing by trusting our gut microbes

Anusha, Jayaraman and Pettersson, Sven * (2022) Happy ageing by trusting our gut microbes. Biochemical and Biophysical Research Communications, 633. pp. 88-91. ISSN 0006-291X

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Official URL: https://doi.org/10.1016/j.bbrc.2022.09.026

Abstract

The human gut microbiota comprises of trillions of micro-organisms in the gut some which secrete metabolites that play a pivotal role in supporting optimal body and organ functions. These dynamic and malleable gut microbes share a bidirectional relationship with their hosts that supports health in an age- and sex-dependent manner. Disruption of the gut microbiota or decrease in their diversity and richness due to unhealthy changes in lifestyle, diet or social disconnection, always results in unwanted outcomes on the host health which fuel chronic disease symptoms including neurodegenerative diseases. Thus, impairment of gut microbiota composition, results in organ decline that accelerates an individual's biological ageing. Here we review evidence supporting the bidirectional relationships between the gut microbiota and biological ageing.

Item Type: Article
Uncontrolled Keywords: gut microbiota; bidirectional relationships; biological ageing; ageing;
Subjects: Q Science > QH Natural history
Q Science > QP Physiology
R Medicine > RA Public aspects of medicine
Divisions: Others > Non Sunway Academics
Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Department of Medical Sciences
Depositing User: Ms Yong Yee Chan
Date Deposited: 31 Jul 2024 13:20
Last Modified: 31 Jul 2024 13:20
URI: http://eprints.sunway.edu.my/id/eprint/2935

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