Low, Zhao Xuan and Rafidah, Lani and Tiong, Vunjia and Poh, Chit Laa * and Sazaly, Abu Bakar and Pouya, Hassandarvish (2023) COVID-19 therapeutic potential of natural products. International Journal of Molecular Sciences, 24 (11). ISSN 1422-0067
Full text not available from this repository.Abstract
Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still one of the leading causes of death in 2022. The availability of COVID-19 vaccines, FDA-approved antivirals, and monoclonal antibodies in low-income countries still poses an issue to be addressed. Natural products, particularly traditional Chinese medicines (TCMs) and medicinal plant extracts (or their active component), have challenged the dominance of drug repurposing and synthetic compound libraries in COVID-19 therapeutics. Their abundant resources and excellent antiviral performance make natural products a relatively cheap and readily available alternative for COVID-19 therapeutics. Here, we deliberately review the anti-SARS-CoV-2 mechanisms of the natural products, their potency (pharmacological profiles), and application strategies for COVID-19 intervention. In light of their advantages, this review is intended to acknowledge the potential of natural products as COVID-19 therapeutic candidates.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COVID-19; SARS-CoV-2; antiviral; therapeutics; natural products; traditional Chinese medicines; plant extracts; |
| Subjects: | Q Science > QD Chemistry Q Science > QK Botany R Medicine > RA Public aspects of medicine |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Centre for Virus and Vaccine Research [dissolved] |
| Depositing User: | Ms Yong Yee Chan |
| Date Deposited: | 03 Jul 2024 06:57 |
| Last Modified: | 03 Jul 2024 06:57 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2719 |
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