Amr Adel, Ahmed Abd El-Aal * and Fairen, Angelin Jayakumar * and Kavita, Reginald * (2023) Dual-action potential of cationic cryptides against infections and cancers. Drug Discovery Today, 28 (11). ISSN 1359-6446
Full text not available from this repository. (Request a copy)Abstract
Cryptides are a subfamily of bioactive peptides embedded latently in their parent proteins and have multiple biological functions. Cationic cryptides could be used as modern drugs in both infectious diseases and cancers because their mechanism of action is less likely to be affected by genetic mutations in the treated cells, therefore addressing a current unmet need in these two areas of medicine. In this review, we present the current understanding of cryptides, methods to mine them sustainably using available online databases and prediction tools, with a particular focus on their antimicrobial and anticancer potential, and their potential applicability in a clinical setting.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cancer; cryptides; infectious disease; peptides; therapeutic agents; |
| Subjects: | Q Science > QD Chemistry R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
| Divisions: | Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Dept. Biological Sciences |
| Depositing User: | Ms Yong Yee Chan |
| Related URLs: | |
| Date Deposited: | 27 Jun 2024 00:52 |
| Last Modified: | 27 Jun 2024 01:02 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2696 |
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