Lalani, S.* and Poh, Chit Laa * (2020) Flavonoids as antiviral agents for Enterovirus A71 (EV-A71). Viruses, 12 (2). p. 184. ISSN 1999-4915
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Poh Chit Lah Flavonoids as antiviral agents.pdf - Published Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (854kB) | Preview |
Abstract
Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents of hand, foot and mouth disease (HFMD), which is prevalent in Asia. Despite much effort, no clinically approved antiviral treatment is available for children suffering from HFMD. Flavonoids from plants serve as a vast reservoir of therapeutically active constituents that have been explored as potential antiviral candidates against RNA and DNA viruses. Here, we reviewed flavonoids as evidence-based natural sources of antivirals against non-picornaviruses and picornaviruses.
| Item Type: | Article |
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| Uncontrolled Keywords: | flavonoids; antivirals; Enterovirus 71 (EV-A71); infectious childhood disease; hand, foot and mouth disease (HFMD); viruses |
| Subjects: | Q Science > QR Microbiology > QR355 Virology |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Engineering and Technology [formerly School of Science and Technology until 2020] > Centre for Virus and Vaccine Research moved to SMLS wef 2021 |
| Depositing User: | Dr Janaki Sinnasamy |
| Related URLs: | |
| Date Deposited: | 10 Feb 2020 05:00 |
| Last Modified: | 01 Oct 2020 09:29 |
| URI: | http://eprints.sunway.edu.my/id/eprint/1215 |
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