Flavonoids as antiviral agents for Enterovirus A71 (EV-A71)

Lalani, S.* and Poh, Chit Laa * (2020) Flavonoids as antiviral agents for Enterovirus A71 (EV-A71). Viruses, 12 (2). p. 184. ISSN 1999-4915

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Official URL: http://doi.org/10.3390/v12020184


Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents of hand, foot and mouth disease (HFMD), which is prevalent in Asia. Despite much effort, no clinically approved antiviral treatment is available for children suffering from HFMD. Flavonoids from plants serve as a vast reservoir of therapeutically active constituents that have been explored as potential antiviral candidates against RNA and DNA viruses. Here, we reviewed flavonoids as evidence-based natural sources of antivirals against non-picornaviruses and picornaviruses.

Item Type: Article
Uncontrolled Keywords: flavonoids; antivirals; Enterovirus 71 (EV-A71); infectious childhood disease; hand, foot and mouth disease (HFMD); viruses
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Others > Non Sunway Academics
Sunway University > School of Engineering and Technology [formerly School of Science and Technology until 2020] > Centre for Virus and Vaccine Research moved to SMLS wef 2021
Depositing User: Dr Janaki Sinnasamy
Related URLs:
Date Deposited: 10 Feb 2020 05:00
Last Modified: 01 Oct 2020 09:29
URI: http://eprints.sunway.edu.my/id/eprint/1215

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