Wong, Jie Jun and Purbojati, Rikky and Tan, Ru San and Pettersson, Sven * and Koh, Angela S (2022) Distinct gut microbiota composition among older adults with myocardial ageing. ESC Heart Failure, 9 (6). pp. 4366-4368. ISSN 2055-5822
Full text not available from this repository.Abstract
Changes in cardiac structure and function occur with ageing and may lead towards ageing-related cardiovascular disease.1 Recent explorations into intestinal microbiota have provided important insights into shifts in microbial composition that occur in response to cardiovascular disease pathogenesis. Several proposed mechanisms include altered gut permeability, endotoxemia, and the systemic effect of metabolites including trimethylamine (TMA), short-chain fatty acids (SCFA), and secondary bile acids.1 However, causal associations between gut microbes and left ventricular (LV) function have yet to be proven. We sought to determine whether gut microbial composition is associated with left ventricular myocardial relaxation, an early manifestation of myocardial ageing, among older adults.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | myocardial; intestinal microbiota; ageing; older adults; cardiovascular disease; |
| Subjects: | Q Science > QH Natural history Q Science > QP Physiology R Medicine > RC Internal medicine |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Department of Medical Sciences |
| Depositing User: | Ms Yong Yee Chan |
| Date Deposited: | 12 Aug 2024 00:44 |
| Last Modified: | 12 Aug 2024 00:44 |
| URI: | http://eprints.sunway.edu.my/id/eprint/3058 |
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