Wu, Yuan Seng * and Lee, Michelle Felicia * and Guad, Rhanye Mac and Fathima, Zahraa Ozeer and Appalaraju, Velaga and Vetriselvan, Subramaniyan and Neeraj, Kumar Fuloria and Shivkanya, Fuloria and Choy, Ker Woon and Lee, Sze Meng and Subash, C.B. Gopinath and Verma, Amita and Lau, Tze Pheng * (2023) Insights on Anticancer Activities, Associated Phytochemicals and Potential Molecular Mechanisms of Quisqualis indica: A Mini Review [Pandangan tentang Aktiviti Antikanser, Fitokimia Berkaitan dan Mekanisme Molekul Berpotensi Quisqualis indica: Suatu Kajian Mini]. Sains Malaysiana, 52 (6). pp. 1749-1758. ISSN 1749-1758
Full text not available from this repository. (Request a copy)Abstract
Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, known as Rangoon Creeper, which can be found abundantly in tropical countries and distributed profusely as a wild shrub. It has been widely used traditionally and scientifically claimed to process various therapeutic activities. It has recently been reported to possess various potential anticancer activities against different cancers. Looking at its availability in almost all seasons and grow fast, it is an arising source of herbal medicine in the discovery of anticancer drugs economically. Besides, Q. indica is enriched with several secondary metabolites of interest, which are responsible for the positive findings for its anticancer potentials. In this review, we aim to decipher and discuss the anticancer activities of Q. indica crude extracts and isolated phytochemicals as evidenced in preclinical models, as well as the associated molecular mechanisms. More preclinical investigations on its anticancer potentials should be conducted before translation to clinical testing.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Anticancer; molecular mechanism; phytochemicals; phytotherapy; Quisqualis indica |
| Subjects: | Q Science > QK Botany R Medicine > RC Internal medicine R Medicine > RS Pharmacy and materia medica |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Department of Medical Sciences Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Dept. Biological Sciences |
| Depositing User: | Ms Yong Yee Chan |
| Related URLs: | |
| Date Deposited: | 22 Jul 2024 12:00 |
| Last Modified: | 22 Jul 2024 12:00 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2841 |
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