Baig, Mirza S. and Thurston, Teresa L. M. and Sharma, Rahul and Atre, Rajat and Saqib, Uzma and Khabiya, Rakhi and Bharti, Shreya and Poh, Chit Laa * (2023) Editorial: Targeting signalling pathways in inflammatory diseases. Frontiers in Immunology, 14. ISSN 1664-3224
Full text not available from this repository.Abstract
Chronic inflammation, characterized by a persistent elevation of circulating pro-inflammatory cytokines, is associated with the pathogenesis of many non-communicable diseases that cause a worldwide health burden and a reduction in quality of life (1). The identification of possible therapeutic targets implicated in the regulation of inflammation offers the opportunity to limit the dangers associated with an imbalance in the inflammatory response (2). Adaptor proteins represent key signaling molecules that regulate the host’s innate immune response to infections, acting as links between receptors and other molecules in several signaling cascades (3, 4). The evident importance of these proteins in the pathophysiology of different chronic inflammatory illnesses makes them attractive therapeutic targets (4).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | inflammatory diseases; targeting signalling; therapeutic targets; MyD88 adaptor-like; MAL; Toll-like receptors; TLR; Toll-interleukin-1 Receptor; TIR; tyrosine kinases; |
| Subjects: | R Medicine > RB Pathology R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Centre for Virus and Vaccine Research [dissolved] |
| Depositing User: | Ms Yong Yee Chan |
| Date Deposited: | 08 Jul 2024 04:04 |
| Last Modified: | 08 Jul 2024 04:04 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2759 |
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