Lim, Felicia Phei Lin and Halcovitch, Nathan R. and Tiekink, Edward R. T. * and Dolzhenko, Anton V (2018) A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines. Tetrahedron, 74 (15). pp. 1868-1879. ISSN 0040-4020
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Tiekink E A New microwave assisted.pdf Download (1MB) | Preview |
Abstract
annulation of 1,3,5-triazine ring onto 5-aminopyrazole-4-carboxylates via a one-pot,multicomponent, microwave-assisted approach. The products were obtained in good yields and high purity. This catalyst-free method was demonstrated to be scalable and highly reproducible in different microwave reactors. Some structural features of the prepared compounds were studied in details using dynamic NMR spectroscopy and X-ray crystallography.
| Item Type: | Article |
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| Uncontrolled Keywords: | Pyrazole; Purine isostere; Multicomponent reaction; Pyrazolo[1,5-a][1,3,5]triazine; Dynamic NMR spectroscopy |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Others > Non Sunway Academics |
| Depositing User: | Dr Janaki Sinnasamy |
| Related URLs: | |
| Date Deposited: | 06 Apr 2018 02:53 |
| Last Modified: | 07 Oct 2020 09:06 |
| URI: | http://eprints.sunway.edu.my/id/eprint/790 |
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