Targeting brain-eating amoebae infections

Khan, Naveed Ahmed * and Ong, Timothy Yu Yee * and Siddiqui, Ruqaiyyah Bano * (2017) Targeting brain-eating amoebae infections. ACS Chemical Neuroscience, 8 (4). pp. 687-688. ISSN 1948-7193

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Abstract

Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae.

Item Type: Article
Additional Information: Embargo 12 months
Uncontrolled Keywords: Protist; free-living amoebae; brain infection; central nervous system; acanthamoeba; balamuthia; naegleria
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology > QR355 Virology
Divisions: Sunway University > School of Science and Technology > Dept. Biological Sciences
Depositing User: Dr Janaki Sinnasamy
Date Deposited: 10 Apr 2017 08:10
Last Modified: 02 Nov 2017 09:22
URI: http://eprints.sunway.edu.my/id/eprint/485

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