Pattern of synonymous codon usage in three strains of human coxsackievirus

Tee, Sim-Hui (2014) Pattern of synonymous codon usage in three strains of human coxsackievirus. Sunway Academic Journal, 11. pp. 1-10. ISSN 1823-500X

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Abstract

The pattern of synonymous codon usage in organisms is not displayed in a random fashion. Some codons are used more frequently than the alternative synonymous codons. This phenomenon is found across species and across genes within a genome. This research investigated the patterns of synonymous codon usage in three strains of human coxsackievirus, using the bioinformatics approach. It was found that the studied strains exhibit a less biased synonymous codon usage pattern, which implies the low expressivity of the genes. Understanding of the patterns of synonymous codon usage is critical to the therapeutic strategies and drug designs to counteract the infection of human coxsackievirus.

Item Type: Article
Additional Information: Author is with Multimedia University. Issue is a special issue on pattern recognition and intelligent applications.
Uncontrolled Keywords: Bioinformatics; viral gene expression patterns; human coxsackievirus; synonymous codon usage bias
Subjects: Q Science > QA Mathematics
Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Divisions: Others > Non Sunway Academics
Depositing User: Ms. Molly Chuah
Date Deposited: 29 Sep 2016 10:06
Last Modified: 29 Sep 2016 10:06
URI: http://eprints.sunway.edu.my/id/eprint/401

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