Chan, Francis K L and Wong, Martin C S and Chan, Andrew T and East, James E and Chiu, Han-Mo and Makharia, Govind K and Weller, David and Ooi, Choon Jin and Limsrivilai, Julajak and Saito, Yutaka and Hang, Dao V and Emery, Jon D and Makmum, Dadang and Wu, Kaichun and Raja Affendi, Raja Ali * and Ng, Siew C (2023) Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia. Gut, 72 (7). pp. 1240-1254. ISSN 1468-3288
Full text not available from this repository. (Request a copy)Abstract
Screening for colorectal cancer (CRC) is effective in reducing CRC related mortality. Current screening methods include endoscopy based and biomarker based approaches. This guideline is a joint official statement of the Asian Pacific Association of Gastroenterology (APAGE) and the Asian Pacific Society of Digestive Endoscopy (APSDE), developed in response to the increasing use of, and accumulating supportive evidence for the role of, non-invasive biomarkers for the diagnosis of CRC and its precursor lesions. A systematic review of 678 publications and a two stage Delphi consensus process involving 16 clinicians in various disciplines was undertaken to develop 32 evidence based and expert opinion based recommendations for the use of faecal immunochemical tests, faecal based tumour biomarkers or microbial biomarkers, and blood based tumour biomarkers for the detection of CRC and adenoma. Comprehensive up-to-date guidance is provided on indications, patient selection and strengths and limitations of each screening tool. Future research to inform clinical applications are discussed alongside objective measurement of research priorities. This joint APAGE-APSDE practice guideline is intended to provide an up-to-date guide to assist clinicians worldwide in utilising non-invasive biomarkers for CRC screening; it has particular salience for clinicians in the Asia-Pacific region.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | clinical decision making; colorectal cancer; screening; tumour markers; |
| Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
| Divisions: | Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > SMLS Admin Others > Non Sunway Academics |
| Depositing User: | Ms Yong Yee Chan |
| Related URLs: | |
| Date Deposited: | 02 Jul 2024 01:30 |
| Last Modified: | 02 Jul 2024 01:30 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2715 |
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