Chung, Felicia Fei Lei * and Zavadil, Jiri (2024) New risk factors and molecular landscapes of hepatic angiosarcoma in the Taiwanese population. The Journal of Pathology, 262 (1). pp. 1-3. ISSN 1096-9896
Full text not available from this repository. (Request a copy)Abstract
Hepatic angiosarcoma is a rare, highly aggressive malignancy of the liver. The tumorigenesis of hepatic angiosarcoma has been relatively understudied in terms of aetiology and molecular properties. A recent study published in The Journal of Pathology revealed a strong association between hepatic angiosarcoma incidence and chronic kidney disease, particularly in end-stage renal disease using population-based data from the National Health Insurance Research Database in Taiwan and an institutional cohort. The study also revealed enrichment in the mutational signature of aristolochic acid exposure and is the first reported observation of this mutational signature in human sarcomas. © 2023 The Pathological Society of Great Britain and Ireland.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | angiosarcoma; aristolochic acid; chronic kidney disease; end-stage renal disease; liver; mutational signature; |
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Others > Non Sunway Academics Sunway University > School of Medical and Life Sciences [formerly School of Healthcare and Medical Sciences until 2020] > Department of Medical Sciences |
| Depositing User: | Ms Yong Yee Chan |
| Related URLs: | |
| Date Deposited: | 12 Jun 2024 00:58 |
| Last Modified: | 12 Jun 2024 00:58 |
| URI: | http://eprints.sunway.edu.my/id/eprint/2662 |
Actions (login required)
 |
View Item |
