Investigation of the effect of 131I on blood parameters for thyroid cancer treatment

Khandaker, Mayeen Uddin * and Hassanpour, Mehdi and Khezripour, Saeedeh and Rezaei, Mohammad Reza and Bazghandi, Atefeh and Hassanpour, Marzieh and Faruque, Mohammad Rashed Iqbal and Bradley, D.A. * (2023) Investigation of the effect of 131I on blood parameters for thyroid cancer treatment. Radiation Physics and Chemistry, 208. ISSN 0969-806X

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Official URL: https://doi.org/10.1016/j.radphyschem.2023.110897

Abstract

Hematopoiesis plays a significant role in mammals’ life. Hematopoietic damage due to radiations of different arrays, such as ionizing and non-ionizing radiations, could lead to external infections, internal infections, and anemia. Different cancers’ treatment using radioactive sources affects the blood parameters (i.e., mature cells, immature cells, and stem cells). In the present paper, the effect of intravascular injection of Iodine-131 (131I) on the blood parameters for thyroid cancer treatment has been investigated utilizing the MCNPX code and Runge-Kutta fourth-order method. The simulation results showed that the accumulated absorbed dose in adult phantom (ORNL whole body phantom) due to normalized intravascular injection of 1 mCi (mCi) of 131I was 1.97 × 10

Item Type: Article
Uncontrolled Keywords: Iiodine-131 irradiation; blood parameters; MGNPX; Runge-Kutta fourth-order; thyroid cancer; ORNL; scintillation detector
Subjects: Q Science > QA Mathematics
Q Science > QC Physics
Q Science > QP Physiology
R Medicine > RC Internal medicine
Divisions: Others > Non Sunway Academics
Sunway University > School of Engineering and Technology [formerly School of Science and Technology until 2020] > Research Centre for Applied Physics and Radiation Technologies [merged with Centre for Carbon Dioxide Capture and Utilization wef December 2023]
Depositing User: Ms Yong Yee Chan
Related URLs:
Date Deposited: 16 Jun 2023 03:48
Last Modified: 16 Jun 2023 03:48
URI: http://eprints.sunway.edu.my/id/eprint/2256

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