Structural vaccinology for viral vaccine design

Mohd Ishtiaq Anasir, * and Poh, Chit Laa * (2019) Structural vaccinology for viral vaccine design. Frontiers in Microbiology, 10. p. 738. ISSN 1664-302X

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Official URL: http://doi.org/10.3389/fmicb.2019.00738

Abstract

Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the design of novel vaccines against challenging viruses such as human immunodeficiency virus (HIV), hepatitis C virus, enterovirus A71, and dengue virus. Recent studies demonstrated that applications of this structural information can solve some of the vaccine conundrums. This review focuses on recent advances in structure-based vaccine design, or structural vaccinology, for novel and innovative viral vaccine design.

Item Type: Article
Uncontrolled Keywords: structural vaccinology; vaccine design; protein structure; epitope; virus
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Sunway University > School of Science and Technology > Centre for Virus and Vaccine Research
Depositing User: Dr Janaki Sinnasamy
Related URLs:
Date Deposited: 06 Sep 2019 09:24
Last Modified: 19 Sep 2019 01:59
URI: http://eprints.sunway.edu.my/id/eprint/1097

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