Mohd Ishtiaq Anasir, * and Poh, Chit Laa * (2019) Structural vaccinology for viral vaccine design. Frontiers in Microbiology, 10. p. 738. ISSN 1664-302X
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Poh CL_Structural Vaccinology for Viral Vaccine Design.pdf - Published Version Available under License Creative Commons Attribution Non-commercial. Download (1MB) | Preview |
Abstract
Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the design of novel vaccines against challenging viruses such as human immunodeficiency virus (HIV), hepatitis C virus, enterovirus A71, and dengue virus. Recent studies demonstrated that applications of this structural information can solve some of the vaccine conundrums. This review focuses on recent advances in structure-based vaccine design, or structural vaccinology, for novel and innovative viral vaccine design.
| Item Type: | Article |
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| Uncontrolled Keywords: | structural vaccinology; vaccine design; protein structure; epitope; virus |
| Subjects: | Q Science > QR Microbiology > QR355 Virology |
| Divisions: | Sunway University > School of Engineering and Technology [formerly School of Science and Technology until 2020] > Centre for Virus and Vaccine Research moved to SMLS wef 2021 |
| Depositing User: | Dr Janaki Sinnasamy |
| Related URLs: | |
| Date Deposited: | 06 Sep 2019 09:24 |
| Last Modified: | 19 Sep 2019 01:59 |
| URI: | http://eprints.sunway.edu.my/id/eprint/1097 |
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